Medically Reviewed by:
Motilium (Domperidone)
Living with nausea can significantly disrupt daily activities. Conditions like gastroparesis slow down stomach emptying, leading to nausea, vomiting, and bloating. Motilium addresses these issues at their source by promoting quicker food passage through the digestive system, making it invaluable for those struggling with slow gastric emptying.
Over-the-counter remedies might offer temporary relief, but Motilium (Domperidone) provides a more robust, long-term solution. Approved by health authorities, its efficacy makes it a preferred choice for managing chronic nausea and related symptoms. Patients with conditions such as migraines or side effects from other medications can also benefit from Motilium.
Please note that Motilium is a prescription medication. You will need to consult your doctor to determine if it is the right option for you.
Medically Reviewed by:
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Medically reviewed by Dr. Samuel Maaiah, PharmD
Last updated: April 10, 2024

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.
When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.
Discover the Benefits of Motilium
Motilium (Domperidone) is a trusted solution for combating nausea and vomiting. It’s especially useful for symptoms linked to gastroparesis and other gastric issues. Available in 5mg and 10mg doses, this medication enhances stomach and intestinal contractions by blocking dopamine receptors in the brain. This effectively reduces the sensation of sickness. Motilium’s popularity stems from its proven ability to improve gastric motility and alleviate discomforting gastrointestinal symptoms.
Motilium Pricing
Dealing with nausea shouldn’t strain your finances or have long delivery waiting times. At CanadianPharmacyOnline.com, Motilium is available at up to 90% less than you might find elsewhere, with tablets starting as low as $0.50. Our platform offers various doses from reputable manufacturers. This allows you to compare and choose the best option for your needs.
Our convenient home delivery service lets you receive your medication promptly, ensuring you stay on track with your treatment. Enjoy significant savings and ease of use with Canadian Pharmacy Online. Shop your prescription online, today!
Motilium FAQ
How Quickly Does Motilium Work?
Motilium usually begins to relieve nausea within 30 to 60 minutes after taking the medication.
Are There Any Side Effects of Taking Motilium?
Common side effects may include dry mouth, abdominal cramps, and dizziness. As with all medications, side effects vary by individual.
Can Anyone Take Motilium?
Motilium is not suitable for individuals with certain medical conditions. This includes gastric bleeding, obstruction, or perforation, or for those with allergies to domperidone. Always consult your healthcare provider before starting any new medication.
How Does Canadian Pharmacy Online Ensure the Quality of Motilium?
Canadian Pharmacy Online is a licensed and certified pharmacy committed to strict health authority standards. We ensure all medications, including Motilium, are safe and effective.
Can Motilium Be Taken with Other Medications?
Motilium may interact with medications that affect heart rhythm or are processed by the same liver enzymes. It’s important to inform your healthcare provider about all medications you are taking. This includes over-the-counter drugs and herbal supplements, to prevent potential interactions.
Say Goodbye to Nausea
Step into a life free from nausea without breaking the bank with Canadian Pharmacy Online. Create an account with us today, upload your prescription, and have Motilium delivered straight to your door.
Order Online
How to buy Domperidone online?
Motilium (Domperidone) can be ordered online through CanadianPharmacyOnline.com or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.
Is a prescription required?
Yes, a valid prescription from your doctor is required. Motilium (Domperidone) is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.
What is the maximum amount that can be ordered?
A 90-day supply is the maximum amount that can be ordered at one time. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider. Refills are kept on file for future orders.
Is it safe to order from Canadian Pharmacy Online?
Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.
Motilium Cost
How much does Motilium (Domperidone) cost?
At CanadianPharmacyOnline.com, we make sure to keep drug prices low. You can view the Motilium (Domperidone) cost savings below:
Domperidone 10mg – 100 Tablets
- Average US retail price – N/A
- Our price – $45.00
We provide only generic Motilium (Domperidone) 10 mg tablets here at Canadian Pharmacy Online. A quantity of 100 tablets of Motilium (Domperidone) costs $45.00, which comes out to $0.45 per unit.
Below shows the price comparison of generic Motilium (Domperidone) 10mg at a quantity 100 tablets between the average U.S. retail price and Canadian Pharmacy Online price.
What is the lowest price of Motilium (Domperidone) per unit?
Lowest Price Per Unit: $0.17/unit for Motilium (Domperidone) 10mg tablets
Is this price for Motilium (Domperidone) without insurance?
The prices mentioned above are without insurance. Unfortunately, we are not able to process insurance claims. However, we will give you an official receipt that you can use to apply for reimbursement with your insurer. We are unable to adjudicate with US insurance providers.
Why is Motilium (Domperidone) cheaper from Canada than from the United States?
The cost of medications ordered from India, Canada, and Turkey are internally controlled by the respective governments. The US is a free market economy which is why the price differs since pharmaceutical suppliers can charge what they consider appropriate for the product. As a result, we can offer lower prices to our patients as we receive medications from these countries.
Motilium Coupon
Is there an Motilium (Domperidone) coupon available?
Sorry, we do not have an Motilium (Domperidone) coupon available at this time.
Motilium Generic
Is there a lower cost generic Motilium (Domperidone) available?
Motilium (Domperidone) is available as a generic alternative.
How much cheaper is generic Motilium (Domperidone)?
Generic Motilium (domperidone) is about 40-60% cheaper than brand Motilium at a quantity of 100 tablets.
What is the difference between brand and generic Motilium (domperidone)?
There is no difference between generic and brand Motilium. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.
Shipping
Is shipping available to the United States?
Yes. Your Motilium (Domperidone) will be shipped from Mauritius to the US in 10 to 18 business days or from Canada in 7 to 10 business days. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.
How much does shipping cost?
Standard shipping is free.
Is express shipping available?
If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.
Refill Rx
How to refill a prescription?
Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.
You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.
Are prescriptions automatically refilled?
We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.
Drug Information
About Motilium (Domperidone)
What is Motilium (Domperidone) ?
Motilium (Domperidone) is a prescription medication that is classified as a dopamine antagonist and antiemetic.
Uses
What is Motilium used for?
It is used for the treatment of abnormal gastric motility associated with diabetic gastroparesis and chronic and subacute gastritis.
How does it work?
It exerts its effects by increasing lower esophageal pressure, improving antroduodenal motility, and speeding gastric emptying.
Directions
How do I take Motilium (Domperidone) ?
Motilium (Domperidone) should be taken as directed by your physician. It should be taken at least 30 minutes before a meal.
What dosages are available?
Motilium (Domperidone) is available as brand 5mg and 10mg tablets.
What is the recommended dosage?
It is typically dosed 10mg three times daily but take as directed by your provider.
What is the maximum dosage?
The maximum recommended dosage is 30mg/day.
What if I miss a dose?
If you forget to take Motilium (Domperidone), skip the missed dose and take the dose at your next scheduled time.
Warnings & Precautions
What should you know before you take Motilium (Domperidone)?
Cardiac arrhythmias, cardiac arrest, and sudden death were associated with the intravenous form of domperidone but there have also been similar reports with the oral form of domperidone. Use is not recommended in patients with established heart conditions
To be eligible to receive domperidone, patients must have failed other standard therapies.
QT prolongation, including torsades de pointes have been reported especially when used concomitantly with CYP3A4 inhibitors and/or other QT-prolonging drugs
Tablets contain aspartame which may be harmful to phenylketonuric patients
Tablets and film coated tablets contain lactose which may be harmful to patients who have lactose intolerance
Avoid use in pregnancy
Dose may need to be renally adjusted for impairment
Use not recommended in patients aged less than 16
Side Effects
What are the side effects of Motilium (Domperidone)?
Common side effects include (1 – 10%):
- Xerostomia
Serious side effects include:
- Prolonged QT-interval
- Ventricular arrhythmias
- Sudden cardiac death
- Allergic reaction
Speak to your doctor for a full list of side effects.
Interactions
Does this medication interact with other drugs, foods, or alcohol?
Concomitant use of moderate or strong CYP3A4 inhibitors can lead to increased concentrations of domperidone
Concomitant use with lithium may increase extrapyramidal symptoms, cause encephalopathy and brain damage
Concomitant use of QT-Prolonging medications
Speak with your doctor for a full list of possible interactions.
Storage
How should this medication be stored?
Motilium (Domperidone) should be stored in the original packaging at a temperature not exceeding 30°C
Pharmacist Tips
- Given the risks of this medication, ensure you have failed other therapies before taking this medication
- Provide your doctor with a complete list of your current medications and full medical history as this medication can have many interactions that can be fatal if not managed appropriately
- Report any new medications or new over-the-counter medications promptly to your doctor
- Use the lowest dose for the shortest duration possible to minimize adverse effects
- Be mindful what dose you are taking because as you approach the higher end of the dosing limit, the risk for adverse effects/events increase
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Domperidone FAQ
What is Domperidone used for?
It is an anti-emetic which is used to treat patients experiencing nausea and/or vomiting symptoms. It is typically reserved for patients in palliative care with stomach pain.
Why is Domperidone banned in the US?
It was banned due to the risk of fatal cardiac arrhythmias. It is available for use in the US under a strict protocol provided by the FDA where a patient has failed multiple, proven therapies and are still symptomatic.
Can Domperidone cure gastroparesis?
It has shown to have beneficial effects in the treatment of gastroparesis but there is no cure for gastroparesis.
Does Domperidone shorten life span?
Due to the adverse effects associated with this medication, it can decrease the overall quality of life and also increase the risk of potentially fatal complications.
What drugs interact with Domperidone?
Many drugs have the potential to interact with Domperidone. Ask your pharmacist or doctor for a full list of interacting medications.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.