Trelegy Ellipta (Fluticasone/Umeclidinium/Vilanterol)

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Select your dosage below to view Trelegy inhaler cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Trelegy Ellipta
Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate
Trelegy Ellipta
Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate
Trelegy Ellipta
Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate
Trelegy Ellipta
Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate


Medically reviewed by Dr. Samuel Maaiah, PharmD

Last updated: April 10, 2024

Medically Reviewed by Pharmacist Samuel Maaiah, PharmD

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

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Order Online

How to buy Trelegy Ellipta online?

Trelegy Ellipta can be ordered online through or by calling 1-800-828-4489 and speaking to our customer support.

The chat feature can also be used for support. For more information, please visit the “How to Order” page.

Is a prescription required?

Yes, Trelegy Ellipta  is a prescription medication and can only be sold with a prescription.

To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 90-day supply is the maximum amount that can be ordered at one time. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider. Refills are kept on file for future orders.

Is it safe to order online from Canadian Pharmacy Online?

Absolutely. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. 

Trelegy Ellipta Cost

How much does Trelegy Ellipta cost?

At, we make sure to keep drug prices low.

You can view the Trelegy Ellipta cost savings below with the price comparison between the average U.S. retail price and our price:

Trelegy Ellipta – (1 inhaler)

  • Average US retail price: $779.00
  • Our price: $106.00

What is the lowest price of Trelegy Elliptaper unit?

Lowest Price Per Unit: $2.83/unit for 90 doses of Trelegy Ellipta.

Trelegy price is made affordable from our online pharmacy service.

Is this price for Trelegy Ellipta without insurance?

The listed prices are without insurance. Unfortunately, we cannot accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer since we are unable to adjudicate with US insurance providers.

Why is Trelegy Ellipta cheaper from Canada than from the United States?

The prices of medications ordered from India, Canada, and Turkey are internally controlled by the respective governments. The US is a free market economy which is why the price differs since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we supply medications from these countries.

Trelegy Ellipta Coupon

Is there a coupon for Trelegy available?

Yes, we do you have a Trelegy coupon for an extra discount on your prescription. You can save $15 off your order with coupon code TRELEGY15. Apply coupon at checkout for instant savings and pay less for your prescription with a minimum $150 order.

Trelegy Ellipta Generic

Is there a lower cost generic Trelegy Ellipta available?

Trelegy Ellipta is not available as a generic alternative.

How much cheaper is generic Trelegy Ellipta?

There is currently no generic alternative to Trelegy Ellipta.

What is the difference between brand and generic Trelegy Ellipta?

Once available on the market, there will be no difference between generic and brand Trelegy Ellipta. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file.

Placing a refill order online is made simple by accessing the reorder section in your account. You can also call us and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Trelegy Ellipta

What is Trelegy Ellipta?

Trelegy Ellipta is a prescription medication that is classified as a long-acting beta agonist (LABA).


What is it used for? 

Trelegy Ellipta contains 3 different types of medications formulated in the same inhaler:

  • Inhaled Corticosteroid (ICS) (Fluticasone)
  • Long acting Beta- agonist (LABA) (Vilanterol)
  • Long acting muscarinic antagonist (Umeclidinium)

These medications function to improve the symptoms associated with Chronic Obstructive Pulmonary Disease (COPD) and as a maintenance therapy for patients with asthma. 

This medication should not be used for acute relief of bronchospams or asthma attacks. 

How does it work?

The fluticasone component acts an anti-inflammatory agent, the umeclidinium inhibits the M3 receptors which causes bronchodilation, and the vilanterol increases the cyclic adenosine monophosphate levels, which causes the bronchial smooth muscles to relax. 


How do I take Trelegy Ellipta?  

Consult the provided package instructions for complete directions, listed is a set of abridged directions:

  • The inhaler device provided has a grey cover, each time this cover is rotated to the side of the mouthpiece there will be a distinct click. This action primes a dose. Ensure you do not return the cover back to the original position without using your dose as this will waste a dose. It is not possible to accidently take a double dose. 
  • Once you have exposed the mouthpiece appropriately, exhale fully away from the inhaler, place your lips around the mouthpiece and inhale slowly and deeply through your mouth. 
  • Ensure you do not cover the air vents with your fingers. 
  • Remove the inhaler from your mouth and hold your breath for as long as is comfortable (3 to 4 seconds) 
  • Exhale slowly and gently away from the inhaler, return the cover back to its original position and store appropriately. 
  • The counter should be reduced by 1 after the dose. 
  • Rinse your mouth with water, do not swallow the water.

What dosages are available?

Trelegy (fluticasone/umeclidinium/vilanterol inhalation powder) is offered as an inhaler (100 mcg/62.5 mcg/ 25mcg)

What is the recommended dosage?

You should take Trelegy as directed by your physician, generally it is dosed 1 inhalation daily. 

What is the maximum dosage?

The maximum recommended dosage is 1 inhalation of fluticasone furoate 200 mcg/umeclidinium 62.5 mcg/vilanterol 25 mcg daily. 

What if I miss a dose?

If you miss a dose you should take one as soon as you remember, if it is relatively close to when your next dose is due, wait till your scheduled time and take a normal dose, do not take an extra dose to make up for the missed dose. 

Warnings & Precautions

What should you know before you take Trelegy Ellipta (fluticasone/umeclidinium/vilanterol inhalation powder)?

There is data showing that LABA monotherapy can increase risk of serious asthma related events. 

Do not use this medication to treat acute symptom presentation

Do not use this medication in combination with other LABA medications 

Oral candidiasis is a risk associated with this medication, to prevent infection, rinse your mouth with water after each dose.

There is increased risk of pneumonia in patients with COPD using this medication, if you develop signs and symptoms of pneumonia contact your doctor. 

If you experience a paradoxical bronchospasm while taking Trelegy discontinue and switch to an alternative therapy. 

This medication may put you at risk for worsening of infections if you have existing tuberculosis, fungal, bacterial, viral, parasitic infections, or ocular herpes simplex ensure your prescriber is monitoring the progression closely. 

If you are transitioning from an oral corticosteroid to this medication ensure you understand the transition instructions as inappropriate execution can put you at risk for complications.

Patients taking beta-blockers should notify their doctor if they have increased symptoms of increased heart rate, blood pressure, or chest pain. 

Patients at risk for or have existing decreased bone mineral density should have their bone mineral density evaluated regularly.

If you have existing glaucoma or cataracts, notify if you experience worsening symptoms while on this medication. 

If you have existing problems with urinary retention or prostatic hyperplasia notify your doctor if you experience symptom worsening. 

Side Effects

What are the side effects of Trelegy Ellipta?

Some common (≥1%) side effects include:

  • Upper respiratory Tract infection
  • Pneumonia 
  • Bronchitis 
  • Oral Candidiasis
  • Headache
  • Back Pain
  • Arthralgia (Joint pain)
  • Influenza 
  • Sinusitis 
  • Pharyngitis
  • Rhinitis 
  • Dysgeusia
  • Constipation
  • Urinary tract infection
  • Diarrhea
  • Gastroenteritis
  • Oropharyngeal pain
  • Cough 
  • Dysphonia

Speak to your doctor for a full list of side effects.



Does this medication interact with other drugs, foods, or alcohol?

Fluticasone is metabolized by CYP3A4, as a result, medications that are strong inhibitors of this enzyme should be used with caution. 

MAOI’s and TCA should be used with extreme caution as they may potentiate the vascular effect of vilanterol.

Patients on beta-blockers should be cautious about this medication as it may potentiate a bronchospasm or decrease the effectiveness of the beta blocker.


How should this medication be stored?

Trelegy should be stored at room temperature between 68°F and 77°F

Pharmacist Tips

  • If you experience acute symptoms of COPD use your provided emergency inhaler to improve symptoms, DO NOT use Trelegy for these symptoms. 
  • Monitor the frequency that you require doses from your emergency inhaler when using Trelegy as this will help the provider evaluate the effectiveness of your therapy. 
  • Make sure you rinse your mouth after each dose with water as this reduces your risk of developing an infection in your mouth and throat.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Trelegy Ellipta Coupon
Use Trelegy coupon code to get $15 discount. Minimum $150 purchase required. *Coupon codes are one-time use and cannot be combined.

Trelegy Ellipta FAQ

Can I just stop taking Trelegy?

Do not discontinue Trelegy unless otherwise instructed by your provider as this puts you at an increased risk for significant worsening symptoms. 

Can you take Trelegy more than once a day?

Trelegy should be dosed as instructed by your provider. Trelegy was not studied as a more than once daily medication it should not be used more than once daily as this could put you at risk for side effects. 

How quickly does Trelegy work?

The effectiveness of Trelegy is generally monitored through FEV1. Some patients show significant improvement after the first dose, others may take a few weeks to notice significant effects. 

Can people with asthma take Trelegy?

Yes, Trelegy carries an FDA indication as a maintenance therapy for patients with asthma. This medication is not indicated for the treatment of acute asthma attacks, use your provided emergency inhaler to treat these symptoms. 

Is Trelegy a DPI?

Yes, Trelegy is what is known as a dry powder inhaler (DPI). 

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.