Spiriva (Tiotropium)

Rx Prescription Required

Select your dosage below to view Spiriva cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Spiriva Handihaler
Tiotropium Bromide Monohydrate
Tiotropium Rotacaps with Rotahaler (Generic)
Tiotropium Bromide Monohydrate
Spiriva Handihaler
Tiotropium Bromide Monohydrate
Spiriva Handihaler
Tiotropium Bromide Monohydrate
Tiotropium Handihaler (Generic)
Tiotropium Bromide Monohydrate


Medically reviewed by Dr. Samuel Maaiah, Pharm D

Last updated: April 10, 2024

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

Order Online

How to buy Spiriva (Tiotropium) online?

Spiriva (Tiotropium) can be ordered online through CanadianPharmacyOnline.com or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.

Is a prescription required?

Yes, a valid prescription from your doctor is required. Spiriva (Tiotropium) is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Is it safe to order from Canadian Pharmacy Online?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Spiriva Cost

How much does Spiriva cost?

Spiriva Handihaler 18mcg – 30 Doses

  • Average US retail price – $537.00
  • Our Price – $75.00

At CanadianPharmacyOnline.com, we make sure to keep drug prices low.

You can view the Spiriva HandiHaler cost savings above with the price comparison between the average U.S. retail price and Canadian Pharmacy Online price

What is the lowest price of Spiriva (Tiotropium) per unit?

Lowest Price Per Unit: $1.44/unit for Spiriva HandiHaler 18 mcg inhaler.

Spiriva inhaler cost is made affordable with our online pharmacy service.

Is this price for Spiriva (Tiotropium) without insurance?

The prices mentioned above are without insurance. Unfortunately, we cannot accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are unable to adjudicate with US insurance providers.

Why is Spiriva (Tiotropium) cheaper from Canada than from the United States?

The prices of medications ordered from Canada are cheaper because drug prices are negotiated and regulated. The US is a free market economy which is why the price may differ since pharmaceutical suppliers can charge what they determine appropriate for the product. As a result, we can offer lower prices to our patients as we utilize medications from these countries.

Spiriva Coupon

Is there a coupon for Spiriva available?

Yes, we do you have a Spiriva coupon for an extra discount on your prescription. You can save $10 off your order with coupon code SPIRIVA10. Apply coupon at checkout for instant savings and pay less for your prescription with a minimum $50 order.

Spiriva Generic

Is there a lower cost generic Spiriva HandiHaler available?

There is a more affordable generic alternative available.

How much cheaper is generic Spiriva HandiHaler?

Generic Spiriva HandiHaler (Tiotropium) is $38 cheaper than brand Spiriva HandiHaler. 

What is the difference between brand and generic Spiriva HandiHaler?

There is no difference between generic and brand Spiriva HandiHaler. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.

You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Spiriva (Tiotropium)

What is Spiriva HandiHaler? 

Spiriva HandiHaler (Tiotropium) is a prescription medication that is classified as a long acting muscarinic antagonist (LAMA).


What is Spiriva used for? 

It is used as a maintenance therapy for bronchospasms associated with chronic obstructive pulmonary disease (COPD).

How does it work?

It induces bronchodilation by inhibiting the M3 receptor on airway smooth muscle.


How do I take Spiriva HandiHaler? 

DO NOT take the capsules by mouth

To dose, place a capsule in the center chamber of the handihaler device, utilizing the green piercing button on the side of the device, depress it completely once. Put your mouth around the mouthpiece, inhale deeply and slowly. Remove mouth from device and hold your breath for as long as is comfortable, then exhale slowly. Repeat inhalation of the same capsule contents again. Dispose of the remaining contents inside of the Handihaler.

What dosages are available?

Spiriva HandiHaler comes in brand and generic 18 mcg/dose dispensers.

What is the recommended dosage?

You should take as directed by your doctor, generally it is dosed as 2 inhalations of the powdered contents of one capsule once daily.

What is the maximum dosage?

The maximum recommended dosage is 2 inhalations (1 dose)/day.

What if I miss a dose?

If you miss a dose, take it as soon as you remember, do not take more than one dose every 24 hours.

Warnings & Precautions

What should you know before you take Spiriva HandiHaler?

Spiriva Handihaler is not indicated as a rescue medication, refer to your doctors recommendations for an emergency inhaler 

Hypersensitivity Reactions can happen from spiriva, discontinue use if you have swelling of the tongue, patients with a milk hypersensitivity should exercise extra caution. 

Spiriva can cause paradoxical bronchospasms discontinue Spiriva if you have these symptoms 

Patients with existing narrow-angle glaucoma should use Spiriva cautiously as it can worsen symptoms 

Patients may have worsening urinary retention with Spiriva, if you have existing urinary retention you should use this cautiously, notify your doctor if you have worsening symptoms.

Side Effects

What are the side effects of Spiriva HandiHaler ?

Some common (>5% incidence) side effects include:

  • Upper Respiratory tract infection 
  • Dry Mouth 
  • Sinusitis 
  • Pharyngitis 
  • Non-specific Chest Pain
  • Urinary Tract Infection 
  • Dyspepsia 
  • Rhinitis 

Speak to your doctor for a full list of side effects.


Does this medication interact with other drugs, foods, or alcohol?

Patients should avoid use with other anticholinergics since it has not been studied.


How should this medication be stored?

The capsules provided should remain in their original packaging (blister pack) until a single dose is required for usage. DO NOT store capsules in the Handihaler device. Store at room temperature (77°F)

Pharmacist Tips

  • Do Not swallow the capsules provided 
  • Inhale the contents of one capsule twice 
  • Rinse handihaler with warm water, air dry afterwards.
  • It takes approx 24 hours for the device to air dry so ensure you clean it promptly after using
  • Do not use for asthma attacks

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Spiriva Coupon
Use Spiriva coupon code to get $10 discount. Minimum $50 purchase required. *Coupon codes are one-time use and cannot be combined.

Spiriva FAQ

How long does spiriva stay in your system?

The half life of Spiriva dry powder is ~5 to 6 days, so it takes about 25 days for Spiriva to be fully cleared from your system.

How long does it take for Spiriva to work?

In the clinical trials they found patients to have peak effect of Tiotropium 3 hours following the first dose.

What are side effects from Spiriva?

Common side effects include: Upper Respiratory tract infection, dry mouth, sinusitis, pharyngitis, non-specific chest pain, urinary tract infection, dyspepsia, and rhinitis.

Is Spiriva a steroid?

No, it is referred to as a long acting muscarinic antagonist (LAMA).

Can you stop Spiriva abruptly?

Spiriva acts as a maintenance type inhaler, discontinuing this therapy should only be done after discussing it with your doctor as it may be controlling your asthma or COPD symptoms and you may experience an exacerbation if you discontinue it abruptly without a supplement therapy.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.