Rybelsus (Semaglutide)

Rx Prescription Required

Select your dosage below to view Rybelsus cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Rybelsus 3mg
Novo Nordisk
Rybelsus 7mg
Novo Nordisk
Rybelsus 14mg
Novo Nordisk
Rybelsus 3mg
Novo Nordisk
Rybelsus 7mg
Novo Nordisk
Rybelsus 14mg
Novo Nordisk
Rybelsus 3mg
Novo Nordisk
Rybelsus 7mg
Novo Nordisk
Rybelsus 14mg
Novo Nordisk


Medically reviewed by Dr. Samuel Maaiah, PharmD

Last updated: April 10, 2024

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

Order Online

How to buy Rybelsus (semaglutide) online?

Rybelsus (semaglutide) can be ordered online through CanadianPharmacyOnline.com or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.

Is a prescription required?

Yes, a valid prescription from your doctor is required. Rybelsus (semaglutide) is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Is it safe to order from Canadian Pharmacy Online?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Rybelsus Cost

How much does Rybelsus (semaglutide) cost?

Rybelsus 7mg – 30 Tablets

  • Average US retail price – $968.15
  • Our price – $285.00

At CanadianPharmacyOnline.com, we make sure to keep drug prices low. You can view the Rybelsus (Semaglutide) cost savings above with the price comparison of Rybelsus (Semaglutide) between the average U.S. retail price and Canadian Pharmacy Online price

What is the lowest price of Rybelsus (Semaglutide) per unit?

Lowest Price Per Unit: $8.83/unit for Rybelsus (Semaglutide) 7mg tablets

Is this price for Rybelsus (Semaglutide) without insurance?

The listed prices are not including insurance. Unfortunately, we cannot accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are unable to adjudicate with US insurance providers.

Why is Rybelsus (Semaglutide) cheaper from Canada than from the United States?

The prices of medications ordered from Canada are less because their drug prices are negotiated and regulated. The US is a free market economy which is how the price differs since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we acquire medications from these countries.

Rybelsus Coupon

Is there a coupon for Rybelsus available?

Yes, we do you have a Rybelsus coupon for an extra discount on your prescription. You can save $15 off your order with coupon code RYBELSUS15. Apply coupon at checkout for instant savings and pay less for your prescription with a minimum $100 order.

Rybelsus Generic

Is there a lower cost generic Rybelsus (Semaglutide) available?

Rybelsus (Semaglutide) is not available as a generic alternative.

How much cheaper is generic Rybelsus (Semaglutide)?

There is currently no generic alternative to Rybelsus (Semaglutide).

What is the difference between brand and generic Rybelsus (Semaglutide)?

Once available on the market, there will be no difference between generic and brand Rybelsus (Semaglutide). Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.
You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Rybelsus (Semaglutide)

What is Rybelsus (Semaglutide)?

Rybelsus (Semaglutide) is a prescription medication that is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist.


What is Rybelsus used for? 

It is used in addition to diet and exercise to help improve blood sugar control in adults with type 2 diabetes.

How does it work?

It exerts its glucose lowering effects by acting as an agonist at the glucagon-like peptide-1 (GLP-1) receptor which increases insulin secretion and decreases glucagon secretion.


How do I take Rybelsus (Semaglutide)? 

Take Rybelsus (Semaglutide) as directed by your doctor.. You should take Rybelsus (Semaglutide) at least 30 minutes prior to your first meal of the day. Take with 3 oz of plain water. Swallow whole, do not crush or chew the tablets.

What dosages are available?

Rybelsus (Semaglutide) comes in brand 3mg, 7mg, and 14mg tablets.

What is the recommended dosage?

Generally it is dosed 3mg once daily but take as directed by your doctor.

What is the maximum dosage?

The maximum recommended dosage is 1mg/day.

What if I miss a dose?

If you miss a dose it should be skipped and you should take a regular dose the following day.

Warnings & Precautions

What should you know before you take Rybelsus (Semaglutide)?

Pancreatitis was reported in 6 patients during the clinical study (0.1 events/100 patient years). If you experience persistent severe abdominal pain contact your doctor immediately.

The risk of hypoglycemia is increased when patients are also taking other glycemic control agents including insulin. Patients’ dose of insulin may need to be altered to account for this change.

Post-marketing studies have shown that there is a risk Acute Kidney Injury with GLP-1 agonists. Patients with underlying kidney disease should be aware of signs and symptoms of AKI (nausea, vomiting, diarrhea, or dehydration). Routine monitoring of your renal function should be completed.

Side Effects

What are the side effects of Rybelsus (Semaglutide)?

Some common side effects include:

  • Nausea
  • Abdominal pain
  • Diarrhea
  • Decreased Appetite
  • Vomiting
  • Constipation

Speak to your doctor for a full list of side effects.


Does this medication interact with other drugs, foods, or alcohol?

Risk of hypoglycemia when given with Sulfonylurea or insulin products

Rybelsus (Semaglutide) causes delayed gastric emptying and may as a result alter the absorption of oral medications. Rybelsus (Semaglutide) should not be taken at the same time as other oral medications. Levothyroxine exposure was increased by 33% when taken with Rybelsus (Semaglutide).


How should this medication be stored?

Store at 68° to 77°F (20 to 25°C)

Pharmacist Tips

  • Rybelsus (Semaglutide) is not for people with type 1 diabetes
  • Rybelsus (Semaglutide) works best when taken at least 30 minutes prior to eating your first meal of the day. Other oral medications can be taken at least 30 minutes after taking Semaglutide.
  • Take Semaglutide on an empty stomach with 4 oz of plain cool water.
  • Monitor your blood sugar regularly and talk to your doctor if you have concerns with hypoglycemia especially if you also utilize insulin products.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Rybelsus Coupon
Use Rybelsus coupon code to get $15 discount. Minimum $100 purchase required. *Coupon codes are one-time use and cannot be combined.

Rybelsus FAQ

How much does Rybelsus (Semaglutide) lower A1C?

In clinical trials, patients had an A1C lowering effect between 1.2-1.4% depending on dose at week 26 of therapy.

When is the best time to take Rybelsus (Semaglutide)?

The best time to take Semaglutide would be 30 minutes prior to your first meal of the day with 4oz glass of water.

Does Rybelsus (Semaglutide) make you feel full?

Yes, Semaglutide can make you feel full. GLP-1 agonists act by slowing gastric emptying, stimulating insulin secretion, and reducing glucagon secretion which makes you feel full.

Is Rybelsus (Semaglutide) a pill or injection?

Rybelsus (Semaglutide) is formulated as an oral medication not an injection.

Can Rybelsus (Semaglutide) be cut in half?

No, do not crush, chew, or cut the tablet.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.