Advair Diskus (Fluticasone/Salmeterol)

Rx Prescription Required

Advair Diskus is a dual-action inhaler that contains fluticasone propionate and salmeterol. Fluticasone propionate is a commonly prescribed corticosteroid that reduces inflammation in your airways. Salmeterol is a long-acting beta-agonist that helps to relax the muscles around the airways. When combined, these medications can help reduce the risk of asthma attacks. It can also prevent wheezing, chest tightness, and more for patients with COPD or asthma. The generic version of Advair Diskus is Wixela™ Inhub™.

The average price for three 250mcg/50mcg inhalers in the United States is approximately $945. However, you can get your Advair Diskus inhaler for as low as $126.00  for three inhalers. We also offer generic Advair for as low as $85.00. You can save even more with our $15 Advair Diskus coupon when you use the code ADVAIR15 at checkout.

Advair Diskus
Fluticasone Propionate, Salmeterol Xinafoate
Fluticasone/Salmeterol Rotacaps (Generic)
Fluticasone Propionate, Salmeterol Xinafoate
Advair Diskus
Fluticasone Propionate, Salmeterol Xinafoate
Fluticasone/Salmeterol (Generic)
Fluticasone Propionate, Salmeterol Xinafoate
Advair Diskus
Fluticasone Propionate, Salmeterol Xinafoate
Advair Diskus
Salmeterol Xinafoate, Fluticasone Propionate
Fluticasone/Salmeterol (Generic)
Fluticasone Propionate, Salmeterol Xinafoate


Medically reviewed by Dr. Meena Mattamana, PharmD

Last updated: April 10, 2024

Medically reviewed by Dr. Meena Mattamana

Meena Mattamana is Enterprise Pharmacy Regulatory Manager and Medication Safety at the Presbyterian Hospital in New York. She was a pharmacy student at the University of Colorado who has had clinical experiences in both community and ambulatory care settings. Her pharmacy interests include administration, psychiatry, and women’s health. She has experience as a medical information consultant and medical writer along with being a clinic pharmacist.

Linkedin Profile

How to Save on Advair Diskus 

Fill a 90-day Supply

Save big when you fill a 90-day supply of Advair Diskus online. This allows you to get the lowest possible price. 

Buy Online at Canadian Pharmacy Online

We offer exceptional Advair Diskus discounts so you can breathe more easily every single day. We also offer free shipping on all your prescriptions and fast delivery. 

Common Questions About Advair Diskus

Who Is an Ideal Candidate for Advair Diskus?

Advair Diskus is specifically designed for patients who haven't adequately controlled their symptoms with a single asthma-control medication and need a combination therapy to manage daily symptoms. However, it is not meant to replace a rescue inhaler in the event of an asthma attack. Be sure to consult your doctor if you have any concerns. 

What Are the Side Effects of Advair Diskus?

Side effects of Advair Diskus include headache, cough, throat irritation, and hoarseness. Some may experience more severe reactions, such as increased blood pressure, fast heart rate, allergic reactions, and bone pain. Consult with a healthcare provider if you are experiencing any adverse effects.

Do I Need a Prescription for Advair Diskus?

Yes, you will need a prescription for Advair Diskus. However, we make it easy to fill your prescription online. All you have to do is create an account at Canadian Pharmacy Online, upload your prescription, and place your order. 

Is There a Difference Between Advair Diskus and the Generic Version? 

There is no difference between Advair Diskus and Wixela™ Inhub™. Both are approved to help individuals manage their daily symptoms of COPD and asthma and contain the same active ingredient. 

Is Advair Diskus Safe for Long-Term Use?

Advair Diskus is safe for long-term use under the supervision of a healthcare provider. Consult with your doctor regularly so they can adjust your asthma and COPD medication as needed. 

Why Fill Your Advair Diskus Prescription at Canadian Pharmacy Online?

At Canadian Pharmacy Online, we've partnered with all the most trusted prescription drug companies to provide you with the medication you need for less. We are fully licensed and certified. Fill your Advair Diskus prescription today. 

Order Online

How to buy Advair Diskus online?

Advair Diskus can be ordered online through or by calling toll-free at 1-800-828-4489 and speaking to customer support.

The chat feature can also be used for support. For more information visit the “How to Order” page. It is simple to get your Advair inhaler at discount prices.

Is a prescription required?

A valid prescription from your doctor is required to order Advair Diskus. Advair Diskus is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription.

The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded . Alternatively, we can reach out to your doctor to attain a valid prescription.


What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on your file for future orders. Typically for this inhaler that would be 180 doses, which is 3 Diskus inhalers.

The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your doctor.

Is it safe to order Advair Diskus from our online pharmacy?

Yes. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee.

We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Advair Cost

How much does Advair Diskus cost?

We ensure that your Advair Diskus price is the most affordable. View the comparison below:

Advair Diskus 250mcg/50mcg – (Brand – 3 Diskus inhalers)

  • Average US retail price: $1888.00
  • Our price: $126.00 USD

Wixela 250mcg/50mcg – (Generic Advar – 3 Diskus inhalers)

  • Average US retail price: $1193.92
  • Our price: $85.00


Is this Advair price without insurance?

Our affordable prices are made available without the need for insurance. Often times our prices are lower than the co-pay for those that have insurance.

We are a solution for both those that have or do not have insurance. Search for your medication to check and compare prices with your local pharmacy.

How much does shipping cost?

We focus on helping you save money. Our standard shipping is FREE.

Based on the medication source selected you will have options at the checkout page to select tracked ($15) or express shipping option ($25) if you so choose. If you need a rush delivery, please reach out to our patient service team to see if that delivery option is available for the medication being ordered.

When you browse the options above, you can note that shipping times differ between the products.


Why is Advair Diskus cheaper from Canada than the United States?

Drug prices are regulated by the government in Canada and other parts of the world like the United Kingdom. This allows for a more affordable cost than in the United States. 

We work hard to source medication from licensed pharmacies around the world to offer you the best value and quickest shipping options.

How to save on Advair Diskus price?

A great way to save on your Advair Diskus prescription is to order a 90-day supply of medication. We offer a lower price per unit when ordering a 3-month supply of medication compared to a 1-month supply. There will be greater discounts and savings when ordering 3 inhalers vs. 1 inhaler.

Alternatively, you can check if there are available pharmacy coupons that can be applied to your order.

Ordering a 90-day supply will provide the greatest prescription savings.

What is the lowest price of Advair per inhaler?

Generic Advair 250mcg/50mcg diskus inhalers are $28.33 per inhaler. Advair generic options are often much cheaper than the brand name option. Browse the options above to see the price differences.

Advair Coupon

Is there a coupon for Advair available?

Yes, we do you have an Advair coupon for an extra discount on your prescription. You can save $15 off your order with coupon code ADVAIR15. This code can also be redeemed for generic Advair coupon as well.

Take advantage Advair Diskus coupon for an additional discount with our already low prices.

Advair Generic

Is there a lower cost generic Advair Diskus available?

Yes, a generic for Advair Diskus is available. It can be known in some regions as Wixela and is available in all the same doses as Advair, 100mcg/50mcg, 250mcg/50mcg, and 500mcg/50mcg combinations.

How much cheaper is generic Advair Diskus?

Typically, generic drugs are about 75- 80% lower in cost than the brand-name. Generic Advair is lower in price and has the same active ingredients as the brand name inhaler.

The generic for Advair is a popular choice for those looking to get the most cost-effective option. a

What is the difference between brand and generic Advair Diskus?

Generic Advair Diskus known as Wixela contains the same active ingredient as brand Advair Diskus. Both medications are indicated to treat the same conditions. Once the patent of a brand medication runs out then other companies can apply and manufacture the generic alternative.


Is shipping available to the United States?

Yes, we ship all across the United States. This saves you time and money by having your medication shipped right to your home.

Is express shipping available?

Medication available from our partner Canadian pharmacy will often have the quickest delivery time. Canadian Pharmacy Advair will ship the fastest to you, though the cost will be more than the “Best Value” option.

The cost for express shipping is $25.00 and has an estimated delivery time of 3-5 business days from Canada to the United States.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy. You can sign into your online account and view your previous orders and see which prescriptions we have on your file. Placing a refill order online is made simple by accessing the re-order section in your account.

You can also call us and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go or in a hurry.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc.

However, we will provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Advair Diskus

What is Advair Diskus?

Advair Diskus is an inhaler that contains a combination of two medications, fluticasone, and salmeterol.


What is Advair Diskus used for?

Advair Diskus is used for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD).

How does it work?

Advair Diskus works in two ways. The medication is a combination product. It has Fluticasone and Salmeterol in it. Fluticasone is an inhaled corticosteroid which helps to reduce inflammation in the lungs.

The Salmeterol component helps to relax the smooth muscle of the bronchioles to increase airflow and make it easier to breathe.


How to use Advair?

This medication is administered twice daily by oral inhalation. Be sure to rinse your mouth with water then spit after each inhalation.

Your provider will go through the technique with you to ensure that you are properly using the inhaler and that the medication is being delivered into the lungs. Use the inhaler exactly as prescribed by your provider.

What dosages are available?

Advair and Wixela are available in 100mcg/50mcg, 250mcg/50mcg, and 500mcg/50mcg combinations. The first number is the dose of fluticasone, the second number is the dose of salmeterol.

What is the recommended dosage?

The dosage depends on what indication is being treated. In asthma, the recommended starting dose is based upon the severity of asthma and will usually be the 100mcg/50mcg or 250mcg/50mcg one inhalation twice daily.

For the treatment of COPD, is the 250mcg/50mcg strength, one inhalation twice daily.

What is the maximum dosage?

The maximum recommended dose of Advair is the 500mcg/50mcg dose, one inhalation twice daily.

What to do if you miss a dose?

If you miss an inhalation, skip that dose, and continue as you normally would.

It is not recommended to take 2 doses together to make up for a missed dose.

Warnings & Precautions

What should you know before you take Advair Diskus?

Precautions while taking this inhaler include asthma-related death, localized infections, pneumonia, thrush, immunosuppression, adrenal suppression, hypersensitivity reactions, cardiovascular effects, and reduction in bone mineral density.

Side Effects

What are the side effects of Advair Diskus?

The side effects include upper respiratory tract infection, sinusitis, cough, headache, nausea and vomiting, diarrhea, and musculoskeletal pain.


Does Advair Diskus interact with other drugs, foods, or alcohol?

This inhaler has the potential to interact with certain antibiotics and antiviral medications. Always let your provider know of all medications that you take both prescription and over the counter.


How should Advair Diskus be stored?

It should be stored between 15°-30°C (59°-86°F) in a dry place and away from any direct heat or sunlight. Be sure to keep this medication out of the reach of children.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Advair FAQ

Is Advair a steroid inhaler?

Yes. It contains two medications, one of which is called fluticasone. Fluticasone is an inhaled corticosteroid.

What does Advair do for the lungs?

It helps patients with asthma and COPD by reducing inflammation in the lungs as well as relaxing airway muscles to make it easier to breathe.

Is Advair a good inhaler?

It is considered a good inhaler because it has two types of medications, fluticasone, and salmeterol. These medications together help to treat different pathways of asthma and COPD diseases to give the patient relief and make it easier to breathe.

What is the difference between Advair and albuterol?

Advair is an inhaler that patients use daily to control their asthma or COPD. Albuterol is also an inhaler; however, it is used as a rescue inhaler when the patient is having difficulty breathing or doing and activity that requires heavy breathing. It is intended to be used only as needed, and not scheduled every day.

How quick does Advair Diskus work?

Patients may start to feel the benefits of this inhaler as soon as 30 minutes after inhalation, however it may take up to a week or more to feel the full benefits.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.