Ranexa (Ranolazine)

Rx Prescription Required

Select your dosage below to view Ranexa cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Ranexa 500mg
A. Menarini Pharma
Ranolazine ER 500mg
Sun Pharmaceuticals Ltd
Ranolazine ER 1000mg
Ranexa 375mg
A. Menarini Pharma
Ranexa 500mg
A. Menarini Pharma
Ranexa 750mg
A. Menarini Pharma


Medically reviewed by Dr. Samuel Maaiah, PharmD

Last updated: April 10, 2024

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

Order Online

How to buy Ranexa (ranolazine) online?

Ranexa (ranolazine) can be ordered online through CanadianPharmacyOnline.com or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.

Is a prescription required?

Yes, a valid prescription from your doctor is required. Ranexa (ranolazine) is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Is it safe to order from Canadian Pharmacy Online?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Ranexa Cost

How much does Ranexa cost?

Ranolazine ER 500mg (Generic) –

  • Average US retail price (90 Tablets) – $498.43
  • Our price (100 Tablets) – $60.00

At CanadianPharmacyOnline.com, we make sure to keep drug prices low.

You can view the Ranexa (Ranolazine) cost savings above with the price comparison of generic Ranexa (Ranolazine) between the average U.S. retail price and Canadian Pharmacy Online price.

What is the lowest price of Ranexa (Ranolazine) per unit?

Lowest Price Per Unit: $0.47/unit for generic Ranexa (Ranolazine) 500mg tablets

Is this price for Ranexa (Ranolazine) without insurance?

The listed prices are without insurance. Unfortunately, we cannot accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are also unable to adjudicate with US insurance providers.

Why is Ranexa (Ranolazine) cheaper from Canada than from the United States?

The prices of medications ordered from Canada cost less because drug prices are negotiated and regulated. The US is a free market economy which is why the price differs since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we utilize medications from these countries.

Ranexa Coupon

Is there a coupon for Ranexa available?

Yes, we do you have a Ranexa coupon for an extra discount on your prescription. You can save $10 off your order with coupon code RANEXA10. Apply coupon at checkout for instant savings and pay less for your prescription with a minimum $100 order.

Ranexa Generic

Is there a lower cost generic Ranexa (Ranolazine) available?

Ranexa (Ranolazine) is available as a generic alternative.

How much cheaper is generic Ranexa (Ranolazine)?

Generic Ranexa (Ranolazine) is $70 cheaper than brand Ranexa at a quantity of 100 tablets (compared to brand Ranexa at a quantity of 60 tablets).

What is the difference between brand and generic Ranexa (Ranolazine)?

There is no difference between generic and brand Ranexa (Ranolazine). Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

Standard shipping is free.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.
You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Ranexa (Ranolazine)

What is Ranexa (Ranolazine)? 

Ranexa (Ranolazine) is a prescription medication that is classified as an antianginal and cardiovascular agent.


What is it used for? 

Ranexa (Ranolazine) is indicated for the treatment of chronic angina.

How does it work?

It inhibits the cardiac late sodium current and prolongs the ventricular action potential.


How do I take Ranexa (Ranolazine)? 

Take Ranexa (Ranolazine) as directed by your doctor; may be taken with or without food, do not crush, break, or chew the tablets.

What dosages are available?

Ranexa (Ranolazine) is available in brand, extended release 375mg, 500mg, and 750mg tablets and generic, extended release 500mg and 1000mg tablets.

What is the recommended dosage?

Generally dosed 500mg twice daily but take as directed by your doctor.

What is the maximum dosage?

The maximum recommended dosage is 2,000mg/day.

What if I miss a dose?

If you miss a dose of Ranexa (Ranolazine), wait to take your next dose at your regular time. Do not make up for the missed dose. Do not take more than 1 dose at a time.

Warnings & Precautions

What should you know before you take Ranexa (Ranolazine)?

Risk for QTc interval Prolongation, if you have more than one doctor ensure that they are made aware that you are taking Ranexa (Ranolazine) as prescribing additional medications that can prolong your QTc interval can put you at significant health risks.

Acute Renal Failure has been observed in some patients with preexisting severe renal impairment (CrCl <30mL/min). Routine monitoring of your renal function should be performed upon initiation and periodically there after if your baseline renal function is <60mL/min.

Side Effects

What are the side effects of Ranexa (Ranolazine)?

Some common side effects include:

  • Dizziness
  • Headache
  • Constipation
  • Nausea

Speak to your doctor for a full list of side effects.


Does this medication interact with other drugs, foods, or alcohol?

Ranexa (Ranolazine) is extensively metabolized by CYP3A enzymes in the liver so drugs that are inhibitors/inducers/substrates of CYP3A should be identified and adjusted accordingly.

Strong CYP3A inhibitors: Do not use Ranexa (Ranolazine) if you are taking ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, and saquinavir.

Moderate CYP3A inhibitors: If you take a moderate inhibitor of CYP3A your dose of Ranexa (Ranolazine) should be limited to 500 mg twice daily. Examples include: diltiazem, verapamil, erythromycin, fluconazole, and grapefruit juice or grapefruit containing products.

CYP3A Inducers: Do not use Ranexa (Ranolazine) if you are taking rifampin, rifabutin, rifapentin, phenobarbital, phenytoin, carbamazepine, and St. John’s wort.

Patients taking simvastatin concurrently should be limited to a dose of 20mg once daily.


How should this medication be stored?

Store at room temperature at 25 °C (77 °F)

Pharmacist Tips

  • Ranexa (Ranolazine) is not used to treat acute angina episodes, but rather will help to prevent episodes.
  • Inform your doctor if you start taking any other medications while on Ranexa (Ranolazine)
  • Do not crush, break or chew any of the tablets as this affects the extended release properties of the medication.
  • This medication may cause dizziness so you should be aware of how this medication affects you prior to operating heavy machinery.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Ranexa Coupon
Use Ranexa coupon code to get $10 discount. Minimum $100 purchase required. *Coupon codes are one-time use and cannot be combined.

Ranexa FAQ

How fast does Ranexa (Ranolazine) work?

Some patients will notice significant improvement in a reduction in anginal symptom frequency and exercise thresholds within 2 weeks.

Can you develop a tolerance to Ranexa (Ranolazine)?

In the clinical trials, they observed that the patients did not develop a tolerance over the 12 weeks of therapy and that their decreases in angina frequency and nitroglycerin use was maintained.

Can Renexa make you sleepy?

A common reported side effect with Ranexa (Ranolazine) is Dizziness/drowsiness and is usually dose dependent. If you are still experiencing these side effects talk to your doctor about a potential dosage change.

Does Ranexa (Ranolazine) drop blood pressure?

Ranolazine is an anti-ischemic and antianginal medication, based on clinical trial data the medication has minimal effects on heart rate and blood pressure.

Does Ranexa (Ranolazine) affect kidney function?

Acute Renal Failure has been observed in some patients with preexisting severe renal impairment (CrCl <30mL/min). Routine monitoring of your renal function should be performed upon initiation and periodically thereafter if your baseline renal function is <60mL/min.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.