Trifexis (Spinosad / Milbemycin Oxime)

Rx Prescription Required

Order Trefexis for your dog from our online pharmacy. We offer significant cost-savings plus FREE SHIPPING.

Comfortis Plus for Dogs 10.1-20lbs (4.6-9kg) 270mg/4.5mg
Spinosad, Milbemycin Oxime
Comfortis Plus for Dogs 20.1-40lbs (9.1-18kg) 560mg/9.3mg
Spinosad, Milbemycin Oxime
Comfortis Plus for Dogs 40.1-60lbs (18.1-27kg) 810mg/13.5mg
Spinosad, Milbemycin Oxime
Comfortis Plus for Dogs 5-10lbs (2.3 -4.5kg) 140mg/2.3mg
Spinosad, Milbemycin Oxime
Comfortis Plus for Dogs 60.1-120lbs (27.1-54kg) 1620mg/27mg
Spinosad, Milbemycin Oxime

Buy Trifexis Online

Trifexis is sold at a very cheap price at and you can use a valid prescription to place your order on our website. You can call us on 1-800-828-4889 to place an order for the drug. You can also order directly from our online pharmacy by selecting the dosage based on your Trifexis prescription.

Our customer care agents are reliable and you can get in touch with them via live chat.  The How to Order section of our website can guide you about the ordering process.

Dosages Available

We offer only the brand option of Trifexis on our online pharmacy. The available dosage strengths are 140/2.3mg, 270/4.5mg, 560/9.3mg, 810/13.5mg, and 1620/27mg. the brand Trifexis is available as a pack size of 6 tablets.

Trifexis Price

We offer low prices on pet meds online, for instance 6 tablets of Trifexis 140/2.3mg cost $110 without coupon or insurance. We offer free shipping to all our customers.

Shipping Time

We will ship your order from Mauritius to the United States in 10 to 18 business days.  We will also send you a notification email about the shipping immediately your order ships.  You will not be asked to pay for shipping when you order Trifexis from our online pharmacy.

Trifexis Information

Trifexis is a chewable tablet formulated for killing fleas and for preventing flea infestation. It also protects against heartworms. It is also useful for treating and controlling several adult worms like

  • Whipworm
  • Roundworm
  • Hookworm

It is tasty and, therefore, easy to use and attractive to the pet. Additionally, the drug is effective against various parasites and it works effectively.  You must not administer this drug to your pet except if a vet doctor prescribes it. The drug is only formulated for dogs and not of any other pet. It should also not be taken by humans.  It is very easy to use and the dog will find it easy to chew.

Recommended Use

Trifexis is a prescription drug and should only be used according to the prescription of the vet doctor. The tablet should be given once in a month. It can be administered to the dog like any other oral medication, added to its food, or chewed by the dog. It is advisable to re-dose the dog if it vomits less than one hour after administration. Find out if your dog is lactating or pregnant first before you administer the drug to it.  There is no study yet about its safety on lactating and pregnant dogs.

Side Effects

Some of the side effects are:

  • Vomiting
  • Loss of appetite
  • Decreased activity or lethargy
  • Diarrhea
  • Cough
  • Increased thirst
  • Increased cough
  • Vocalization
  • Hyperactivity
  • Itching

You should report the side effects to your vet doctor when they come up.


  • The drug should only be administered to dogs only and not to any other pet
  • It should never be given to dogs younger than 8 weeks and does not weight up to 5 lbs
  • You should use it with caution in dogs that have pre-existing epilepsy. It should also be used with caution in breeding females


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