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Tresiba vs Toujeo! Which Long-Acting Insulin Is Right for You?

In recent years with many medical advances, diabetes management is easier than ever. This means you have more options for controlling your blood glucose levels. But, which insulin is right for you?

If you are considering long-acting insulin medications keep reading. This guide will detail the differences between Tresiba vs Toujeo to help find the correct treatment for you.

We will address side effects, pricing, and how to choose the right long-acting insulin. Also, we will walk you through how to purchase your medication and have it shipped to your door for free through our online pharmacy.

Tresiba vs Toujeo: Which Long-Acting Insulin Is Right for You?

Tresiba and Toujeo are both long-acting types of insulin, but they are not the same. Both of these medications are designed for the management of diabetes but have different risks and features. Here are the specifics of each medication:


Tresiba is an FDA-approved form of ultra long-acting insulin used by Type 1 and Type 2 diabetics ages 1 and older to manage and control their condition. Long-acting insulin is taken one time a day to keep insulin and glucose levels steady throughout the day into the night. This medication is given subcutaneously (injected under the skin) from a vial draw up in a syringe or with a FlexTouch pen.

Tresiba works for up to 42 hours. The dosage and how many times you need to administer a dose of Tresiba is determined by your doctor.


Similar to Tresiba, Toujeo is a type of long-acting insulin that is used by children (age 6 and older) with Type 1 diabetes and adults with Type 1 and Type 2 diabetes to mimic the body’s natural insulin release in response to increased blood glucose.

Toujeo is injected once a day under the skin of the stomach, thigh, or upper arm. It starts working after several hours and is slowly absorbed over a 24 hour period. You shouldn’t adjust your dose or use any other insulin without first consulting your doctor.


Hypoglycemia is a significant concern when using insulin. Common indications of hypoglycemia (low blood sugar) are shakiness, anxiety, chills, confusion, irritability, hunger, lightheadedness, rapid heartbeat, and pale skin. Monitor blood glucose levels regularly when using Tresiba or Toujeo.

Neither medication should be administered via an insulin pump, as this increases the risk of hypoglycemia. Other side effects of Tresiba and Toujeo are:

Side Effects of Tresiba

Tresiba may cause unwanted side effects. When starting any new medication, be aware of the potential side effects, such as:

  • Tingling in hands and/or feet
  • Unexpected weight changes
  • Bloating or fluid retention in the arms and/or legs

If you believe you’re experiencing any side effects, contact your doctor. Life-threatening side effects may result from taking Tresiba such as low blood potassium (hypokalemia) and hypoglycemia. If you have these side effects, call 911 or go to your nearest hospital.

Side Effects of Toujeo 

Like Tresiba and any other new medication you begin, Toujeo has the potential side effects. Side effects include, but aren’t limited to:

  • Nasal congestion
  • Back pain
  • Sore throat
  • Fluid retention in the legs/feet and arms/hands

Both Tresiba and Toujeo have the potential for reactions at the injection site (swelling, redness, irritation) allergic reactions, skin problems (rash, itching, thickening of skin at injection site), weight gain, and headache.

Some types of drugs have negative interactions with long-acting insulin. Thiazolidinediones (TZDs) interact with insulin and could lead to heart failure. Your prescriber must know the medications, vitamins, minerals, and supplements you take in order to limit negative reactions.

Differences Between Tresiba and Toujeo 

There are certain key features that differentiate Tresiba from Toujeo. Those features include:

Tresiba is able to be used by both Type 1 and 2 diabetics age 1 and older; Toujeo is approved for all diabetes, but only if they are age 6 and older.

Clinical studies on diabetic adults and children with Type 1 diabetes suggest that Toujeo may be effective at lowering A1c levels.

Toujeo is a long-lasting insulin but doesn’t work for as long as Tresiba. It lasts for up to 36 hours. Tresiba lasts as long as 42 hours

The average retail cost of Tresiba without insurance or a coupon in the United States is about $612.80 for five pens of Tresiba Units/mL.

The average retail cost of Toujeo without insurance or a coupon in the United States is about $464.11 for three pre-filled pens of Toujeo.

You can purchase long-act insulin medications like Tresiba and Toujeo at a very cheap price with our convenient, safe online pharmacy such as 90-Day Meds. You can even save hundreds by switching from 30-day to 90-day medication prescriptions. If you’d like to learn more about how to order your prescriptions online, chat with us or call us at 1-800-828-4889 and we can help you create and place your order

Managing Diabetes

Tresiba and Toujeo are about equally as effective to control glucose levels, but your lifestyle, age, or health may make one a better option than the other. When choosing a medication for controlling your blood glucose levels and diabetes management, you should always consult your doctor.

We Have the Right Long-Acting Insulin For You 

Understanding the differences between Tresiba vs Toujeo is essential to make the right choice for your diabetes management. You can use this new information to discuss Tresiba and Toujeo with your doctor and save money on your prescriptions with 90-Day Meds.

With 90-Day Meds, you can order your prescriptions online and have them shipped straight to you for free. To see the medications we carry and fill your prescription, check out our website, or contact us to see how you can get your medication for cheap.