Asacol (Mesalamine)

Rx Prescription Required

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Mesalamine (Generic)
Mesalamine DR (Generic)
Mesalamine (Generic)


Medically reviewed by Dr. Samuel Maaiah, PharmD

Last updated: April 10, 2024

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

Order Online

How to buy Asacol (Mesalamine) online?

Asacol can be ordered online through or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page on

Is a prescription required?

Yes, a valid prescription from your doctor is required. Asacol is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Is it safe to order Asacol (Mesalamine) from Canadian Pharmacy Online?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Asacol Cost

How much does Asacol (Mesalamine) cost?

Asacol 800mg – 90 Tablets

  • Average US retail price – $1012.49
  • Our price – $133.00

Mesalamine 800mg – 90 Tablets

  • Average US retail price – $611.46
  • Our price – $120.00

Above shows the price comparison of brand and generic Asacol (Mesalamine) 800 mg at a quantity 90 tablets between the average U.S. retail price and Canadian Pharmacy Online price.

We provide both brand and generic Asacol 800 mg tablets. For brand Asacol 800 mg, it costs $133 for 90 tablets, which comes out to be $1.48 per tablet. For generic Asacol 800 mg, it costs $120 for 90 tablets, which comes out to be $1.33 per tablet.


What is the lowest price of Asacol per unit?

Lowest Price Per Unit: $0.87 for Asacol 400mg at a quantity of 924 tablets.

Is this price for Asacol without insurance?

The above listed prices are without insurance. Unfortunately, we cannot accept insurance. However we will give you an official receipt in case it can qualify for a reimbursement from your insurer. We are also unable to adjudicate with U.S. insurance providers.

Why is Asacol cheaper from Canada than the United States?

Prices of medications ordered from Canada, United Kingdom, or Australia are internally controlled by the respective governments. This differs from the US as it is a free market economy and pharmaceutical suppliers can charge what they deem a product is worth. As a result, we can offer lower prices to our patients as we source medications from these countries.

Asacol Coupon

Is there an Asacol (Mesalamine) coupon available?

Sorry, we do not have an Asacol (Mesalamine) coupon available at this time.

Asacol Generic

Is there a lower cost generic Asacol available?

Yes, Asacol is available as a lower cost generic, Mesalamine.

How much cheaper is the generic Asacol?

The lowest price of Mesalamine per unit is $0.45/unit for the 400mg tablets at a quantity of 600 tablets.

What is the difference between brand and generic Mesalamine?

The manufacturer of brand Asacol is Allergen based out of the UK and the manufacturer of generic Mesalamine is Sava Medica Ltd. out of India. Both are considered therapeutically equivalent.


Is shipping available to the United States?

Yes. Asacol will be shipped from the U.K. to the U.S. within 7 to 10 business days. An email notification will be sent to you once the item has been shipped. There are no shipping charges.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

How much does shipping cost?

There are no standard shipping charges. If you wish to have the medication order tracked or expressed then additional charges may apply.

Refill RX

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.

You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Asacol

What is Asacol? 

Asacol is a prescription medication that is classified as a 5-aminosalicylic acid derivative. 


What is Asacol used for? 

It is used for the treatment and maintenance of moderately active ulcerative colitis in adults.

How does it work?

The mechanism isn’t well defined but mesalamine’s potential for blocking cyclooxygenase and prostaglandin synthesis in the colon is theorized to improve inflammation.


How to take Asacol? 

Take your Asacol:

  • Formulated without dibutyl phthalate [DBP]: By mouth on an empty stomach at least 1 hour before or 2 hours after your meal. Do not break, cut, chew, or crush the tablet.

Asacol formulated with DBP has been discontinued in the U.S. for > 1 year, but is still available in other countries, such as Canada.

What dosages are available?

Asacol comes as a brand or generic delayed release 400mg and 800mg tablet.

What is the recommended dosage?

For moderately active ulcerative colitis the manufacturer recommends 1600 mg by mouth three times a day for 6 weeks.

What is the maximum dosage?

The maximum recommended dosage of the Mesalamine 400 mg tablets is 4.8g/day divided into 3 doses.

What if I miss a dose?

Take your dose of Asacol as soon as possible, but if it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule. Never double doses.

Warnings & Precautions

What should you know before you take Asacol?

Use caution in patients with renal dysfunction, a history of renal disease, or those on other nephrotoxic medications.

Use caution in patients that are predisposed to any of these conditions as they have been reported: pericarditis and myocarditis (mesalamine-induced cardiac hypersensitivity reactions).

Use with caution in the elderly (> 65 years of age) as postmarketing reports and uncontrolled studies suggest an increased incidence of blood dyscrasias in those > 65 years of age.

Use with caution in patients with pre-existing skin conditions as severe photosensitivity reactions have been reported.

Evaluate the risk vs benefits of therapy in those with hepatic dysfunction as hepatic failure has been reported with Asacol use.

An intolerance syndrome can develop, with symptoms from cramping, bloody diarrhea, abdominal pain, which can be difficult to differentiate from an exacerbation. Monitor for any worsening of symptoms and stop the medication immediately if this syndrome occurs or is suspected.

Asacol contains ~4.9 mg of iron per 800 mg tablet.

Side Effects

What are the side effects of Asacol?

The most common side effects include:

  • Abdominal pain, constipation, eructation
  • Headache
  • Nasopharyngitis

Speak to your doctor for a full list of side effects that apply to you if you are taking Asacol.


Does this medication interact with other drugs, foods, or alcohol?

Avoid administering Asacol for at least 6 weeks after administration of vaccines containing varicella virus (Risk Category D).

This is not a full list of potential drug-drug-interactions. Speak to your doctor if you have any concerns about drug-drug-interactions.


How should this medication be stored?

Asacol should be stored at room temperature between 20°- 25°C (68°- 77°F).

Pharmacist Tips

  • When taking your medication, be sure to be adequately hydrated to decrease the risk of nephrolithiasis.
  • When taking Asacol, you may find intact, partially intact, and/or tablet shells in your stool.
  • Take your Asacol on an empty stomach 1 hour before or 2 hours after your meal.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Save $10 on your first order!
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Asacol FAQ

Q: Does Asacol suppress the immune system?

No. Asacol is a 5-aminosalicylic acid derivative and does not have any immunosuppressive properties.

Q: Does Asacol affect the immune system?

No. It is a 5-aminosalicylic acid derivative and does not have any immunosuppressive properties.

Q: Does Asacol have aspirin in it?

No. It is a 5-aminosalicylic acid derivative while aspirin is a salicylic acid.

Q: Does Asacol cause constipation?

This medication can cause constipation as one of its side effects.

Q: Does Asacol cause weight gain?

No. It may make you feel well enough to start increasing your food intake.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.