Humalog KwikPen (Insulin Lispro)

Rx Prescription Required

Select your dosage below to view Humalog KwikPen cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Humalog KwikPen 100U 100U/mL
Insulin Lispro
Eli Lilly
Humalog KwikPen 200U 200U/mL
Insulin Lispro
Eli Lilly

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Medically reviewed by Dr. Samuel Maaiah, PharmD

Last updated: February 10, 2022

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

Order Online

How to buy Humalog KwikPen (insulin lispro) online?

Humalog KwikPen can be ordered online through or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.

Is a prescription required?

Yes, a valid prescription from your doctor is required. Humalog KwikPen is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90-days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Is it safe to order Humalog KwikPen (insulin lispro) from Canadian Pharmacy Online?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Humalog KwikPen cost

How much does Humalog KwikPen (insulin lispro) cost?

Humalog KwikPen 100 units/mL – (15mL = 5 pens) 

  • Average US retail price – $708.00
  • Our Price – $175.00

Humalog KwikPen is available only as a brand here at Canadian Pharmacy Online. Above shows the price comparison between the average U.S. retail price and Canadian Pharmacy Online price for a 5 pens (15 mL) of Humalog 100 units/mL.

What is the lowest price of Humalog KwikPen per unit?

Lowest Price Per Unit: $10/unit for Humalog KwikPen 100 units/mL pens 

Is this price for Humalog KwikPen without insurance?

The prices mentioned are without insurance. Unfortunately, we cannot accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are also unable to process claims with US insurance providers.

Why is Humalog KwikPen cheaper from Canada than from the United States?

Drug prices are regulated in Canada and other countries we source medication. The US is a free market economy which is how the price differs since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we obtain medications from these countries.

Humalog KwikPen Coupon

Is there an Humalog KwikPen coupon available?

Sorry, we do not have an Humalog KwikPen coupon available at this time.

Humalog KwikPen Generic

Is there a lower cost generic Humalog KwikPen available?

Humalog KwikPen is available as a generic alternative.

How much cheaper is generic Humalog KwikPen?

Generic  Humalog KwikPen (insulin lispro) is not available at Canadian Pharmacy Online. 

What is the difference between brand and generic Humalog KwikPen?

There is no difference between generic and brand Humalog KwikPen. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. Your Humalog KwikPen will be shipped from Canada to the U.S. within 3 to 5 days. Your medication will be shipped in a packaging made of an insulated cooler with gel and ice packs. An email notification will be sent to you once the item has been shipped. There are no shipping charges.

Is express shipping available?

This medication is shipped express due to it being temperature sensitive.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.
You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Humalog KwikPen (Insulin Lispro)

What is Humalog KwikPen? 

Humalog is a prescription medication that is classified as a rapid-acting insulin.


What is Humalog KwikPen used for? 

It is used for the treatment of type 1 and 2 diabetes mellitus in those 3 years of age and up.

How does it work?

It exerts glucose lowering effects by increasing peripheral glucose uptake into skeletal muscle and fat and also through inhibition of hepatic glucose production.


How do I administer my Humalog KwikPen?

Humalog is a mealtime insulin, which means you will administer it within 15 minutes before your meal or right after. Administer the dose prescribed by your doctor. Only administer if the insulin solution is colorless and clear. Avoid administering cold injections.

Step 1: Check the label on your Humalog KwikPen to make sure that you are using the correct insulin.

Step 2: You will need to attach a new needle with each use. Keep the needle as straight as possible when attaching it to your pen. The Humalog KwikPen uses screw-on or push-on needles.

Step 3: You will need to prime your pen before each injection to remove any air bubbles and ensure that your pen and needle are working correctly. Select a dose of 2 units. You must always prime before your injection to ensure you get the correct dose of insulin.

Remove the outer needle cap and keep it to remove the needle later after your injection. Next, take off the inner needle cap and dispose of it in a sharps container.

Hold the pen upright, with the needle pointing upwards. Gently tap the reservoir to remove any air bubbles that are in the needle.

Hold the pen with the needle pointing upwards. You will then push down on the Dose Knob until it stops and reads “0” in the Dose Window. Hold the Dose Knob for 5 seconds (count to 5 slowly) until you see insulin at the tip of the needle.

  • If you do not see insulin, you will see to prime again, but no more than 4 times.
  • If after this, you still do not see insulin, change the needle and prime again.

Step 4: Make sure that the dose window shows “0” after priming. Then select your prescribed insulin dose in 1-unit steps. If your required dose is > 60 units, you will need to use 2 or more injections.

Step 5: Use the injection method that your doctor or pharmacist showed you. You will either inject the needle subcutaneously in your upper arm, stomach area (abdomen), or thigh (upper leg).

Press the injection button all the way in. Hold the button in that position and slowly count to 10. Then, withdraw the needle.

Step 6: You must remove the needle after each injection and dispose of it appropriately in a sharps container. Place the outer needle cap back on the needle and use it to unscrew the needle from the pen.

Important: Injection sites should always be rotated within the same region (upper arm, stomach area, or thigh). This is to decrease the risk of lipodystrophy.

Dose Selection: A single injection can give a dose between 1 to 60 units. Doses higher than 60 units will require more than 1 injection.

Please also review the full instructions for the use of your Humalog KwikPen that comes with your prescription.

Inject subcutaneously into the thighs, abdomen, arms, or buttock. Injection sites should be rotated within the same region to prevent lipodystrophy or localized cutaneous amyloidosis from occurring. Do not inject into skin with lipodystrophy or localized cutaneous amyloidosis.

Do not dilute your Humalog or mix with other insulins.

What dosages are available?

Humalog KwikPen is available as a brand and generic in 100 units/mL (3 mL pens).

What is the recommended dosage?

The recommended dose varies based on patient-specific factors, refer to your doctor for dosing recommendations.

What is the maximum dosage?

There is no maximum recommended daily dosage.

What if I miss a dose?

A missed dose could result in hyperglycemia. Some symptoms include increased thirst, frequent urination, nausea, vomiting, or stomach pain. Check your blood sugar if you have missed a dose. If it has been roughly within 30 minutes since the missed dose, administer the missed dose. Do not double doses.

Warnings & Precautions

What should you know before you take Humalog KwikPen?

Hypoglycemia is the most common adverse effect.

Hypersensitivity reactions have occurred and can be serious and life-threatening.

Weight gain can occur.

Humalog has not been shown to cross the placenta at the standard clinical doses.

Injection sites need to be rotated to prevent lipodystrophy (skin thickening or pits at injection site) from occurring.

Hypokalemia can occur (risk if higher in intravenous insulin).

Concurrent use with peroxisome proliferator-activated (PPAR)-gamma agonists and thiazolidinediones (TZDs) can cause a dose-related fluid retention and can cause or worsen heart failure.

Side Effects

What are the side effects of Humalog KwikPen?

Some common side effects include:

  • Severe hypoglycemia
  • Antibody development
  • Headache, hyporeflexia
  • Nasopharyngitis , viral respiratory tract infection
  • Accidental injury

Speak to your doctor for a full list of side effects that apply to you if you are using Humalog KwikPen.


Does this medication interact with other drugs, foods, or alcohol?

Avoid use with macimorelin and rosiglitazone (Risk Category X).

This is not a full list of potential drug-drug-interactions. Speak to your doctor if you have any concerns about drug-drug-interactions.


How should this medication be stored?

Unopened and unused Humalog pens should be refrigerated at 2°C to 8°C (36°F to 46°F). Keep the unopened pen protected from light. Do not freeze. If your Humalog has been frozen, do not use it. Do not use your Humalog KwikPen if the solution is cloudy.

Unopened/unused pens can be stored in the refrigerator until the expiration date.

After it has been 28 days from opening, dispose of your Humalog even if there is still insulin left in the pen.

After you have opened and started using your Humalog KwikPen, you can keep your pen at room temperature, below 30°C (86°F). Keep your Humalog KwikPen away from direct sunlight.

Pharmacist Tips

  • Write down the date when you start (opened and used) your KwikPen. Your Humalog medication should be stored in the refrigerator. If unopened and unused, your pen can be stored until its expiration date. If you have opened and used your Humalog KwikPen, dispose of it after 28 days even if there is insulin left.
  • Do not use your insulin if it is cloudy or has been frozen.
  • Signs and symptoms of hypoglycemia can include: sweating, hunger, dizziness/lightheadedness, blurred vision, fast heart beat, shakiness, trouble concentrating/confusion, slurred speech, anxiety, irritability, or mood changes.
    • If your blood sugar < 70 mg/dL, that is hypoglycemia. Follow the “Rule of 15” if this occurs:
    • Consume 15 grams of carbohydrates, which is about 1⁄2 cup of juice or a tablespoon of sugar, honey, or corn syrup.
    • Then, wait 15 minutes and re-check your blood sugar. If it is still < 70 mg/dL, repeat the step again.
    • If the second check is > 70 mg/dL, consume a small portion of protein afterwards.
    • Be sure to check your blood sugar daily and document the readings.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Save $10 on your first order!
Enter Canadian Pharmacy Online coupon code CPO10 to save $10 off your order. Minimum $50 order value. *Coupon codes are one-time use and cannot be combined.

Humalog Kwikpen FAQ

Are Humalog KwikPen and Novolog the same thing?

Humalong (insulin lispro) and Novolog (insulin aspart) are different insulins, but are both rapid-acting insulins.

Is Humalog KwikPen a long-acting insulin?

No. Insulin lispro is a rapid-acting insulin, also known as a “meal-time” insulin.

Is insulin lispro as good as Humalog KwikPen?

Yes. Insulin lispro is the generic version of Humalog.

Is insulin lispro the same as Humalog KwikPen?

Yes. Insulin lispro is the generic version of Humalog.

Is Humalog KwikPen generic?

Humalog KwikPen is the brand name of insulin lispro solution pen-injector.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.