Seroquel XR (Quetiapine)

Rx Prescription Required

Select your dosage below to view Seroquel XR cost and place your order. Save up to 90% and get FREE standard shipping on prescription medication delivered to your door.

Quetiapine SR 300mg
Quetiapine Fumarate
Sun Pharmaceuticals Ltd
Quetiapine XR 50mg
Quetiapine Fumarate
Torrent Pharma Ltd
Quetiapine XR 50mg
Quetiapine Fumarate
UK Various Generics
Quetiapine XR 150mg
Quetiapine Fumarate
UK Various Generics
Quetiapine XR 200mg
Quetiapine Fumarate
UK Various Generics
Quetiapine XR 300mg
Quetiapine Fumarate
UK Various Generics
Quetiapine XR 400mg
Quetiapine Fumarate
UK Various Generics
Seroquel XR 50mg
Quetiapine Fumarate
Seroquel XR 150mg
Quetiapine Fumarate
Seroquel XR 200mg
Quetiapine Fumarate
Seroquel XR 300mg
Quetiapine Fumarate
Seroquel XR 400mg
Quetiapine Fumarate
Quetiapine XR 50mg
Quetiapine Fumarate
Teva Pharmaceuticals
Quetiapine XR 150mg
Quetiapine Fumarate
Teva Pharmaceuticals
Quetiapine XR 200mg
Quetiapine Fumarate
Teva Pharmaceuticals
Quetiapine XR 400mg
Quetiapine Fumarate
Teva Pharmaceuticals


Medically reviewed by Dr. Samuel Maaiah, PharmD

Last updated: April 10, 2024

Dr. Maaiah is a PharmD graduate who has practiced both in pharmaceutical consulting and retail pharmacy. His interests include consulting and the development and approval of new therapeutics. He currently works as a Medical Information Consultant (MIC) and as a retail pharmacist. As a MIC he helps pharmaceutical companies with projects and by consulting as a medical information expert.

When Dr. Maaiah is not working, he enjoys spending time with his family and friends, doing outdoor activities, working out, and reading.

Order Online

How to buy Seroquel XR (Quetiapine XR) online?

Seroquel XR (Quetiapine XR) can be ordered online through or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.

Is a prescription required?

Yes, a valid prescription from your doctor is required. Seroquel XR (Quetiapine XR) is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

What is the maximum amount that can be ordered?

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Is it safe to order from Canadian Pharmacy Online?

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Seroquel XR Cost

How much does Seroquel XR (Quetiapine XR) cost?

Seroquel XR 50 mg (Brand) – 60 Tablets

  • Average US retail price – $605.90
  • Our price – $150.00

Quetiapine XR 50mg (Generic)

  • Average US retail price (90 Tablets) – $660.07
  • Our price (100 Tablets) – $63.00

At, we make sure to keep drug prices low. You can view the Seroquel XR (Quetiapine XR) cost savings above with the price comparison of brand and generic Seroquel XR between the average U.S. retail price and Canadian Pharmacy Online price.

What is the lowest price of Seroquel XR (Quetiapine XR) per unit?

Lowest Price Per Unit: $0.63/unit for generic Seroquel XR (Quetiapine XR) 50mg tablets

Is this price for Seroquel XR (Quetiapine XR) without insurance?

The listed prices above are without insurance. Unfortunately, we do not accept insurance. However, we will give you an official receipt which you can use to apply for reimbursement with your insurance company. We are also unable to adjudicate with US insurance providers.

Why is Seroquel XR (Quetiapine XR) cheaper from Canada than from the United States?

Drug prices are negotiated and regulated in Canada. Because the US is a free market economy, the price differs since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we supply medications from these countries. 

Seroquel XR Coupon

Is there a coupon for Seroquel XR available?

Sorry, we do not have a Seroquel XR coupon at this time.

Seroquel XR Generic

Is there a lower cost generic Seroquel XR available?

Seroquel XR (Quetiapine XR) is available as a generic alternative.

How much cheaper is generic Seroquel XR?

Generic Seroquel XR (Quetiapine XR) $87 cheaper than brand Seroquel XR at a quantity of 100 tablets.

What is the difference between brand and generic Seroquel XR?

There is no difference between generic and brand Seroquel XR. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.


Is shipping available to the United States?

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

How much does shipping cost?

There are no standard shipping fees.

Is express shipping available?

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refill Rx

How to refill a prescription?

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.

You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

Are prescriptions automatically refilled?

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

Drug Information

About Seroquel XR (Quetiapine)

What is Seroquel XR (Quetiapine XR)? 

Seroquel XR is a prescription medication that is classified as an atypical antipsychotic.


What is Seroquel XR used for? 

It is used for the treatment of Schizophrenia, Bipolar I disorder (manic or mixed episodes), Bipolar disorder (depressive episodes), Major depressive disorder, and as adjunctive therapy with antidepressants.

How does it work? ‘

It is theorized to exert its effects by dopamine, serotonin, and norepinephrine receptor antagonism.


How do I take Seroquel XR? 

You can take Seroquel XR with or without food, make sure you swallow the tablets whole, do not crush or chew.

What dosages are available?

Seroquel XR comes in brand and generic 50mg, 150mg, 200mg, 300mg, and 400mg tablets.

What is the recommended dosage?

Take Seroquel XR as directed by your doctor, generally it is dosed once daily at night. The dosage varies per indication for use; ask your doctor for dosing recommendations.

What is the maximum dosage?

The maximum recommended dosage is 800mg/day.

What if I miss a dose?

If you miss a dose, take it as soon as you remember, if it is relatively close to the time for your next dose, wait until then and take a normal dose, do not take an extra dose to make up for the missed dose.

Warnings & Precautions

What should you know before you take Seroquel XR (Quetiapine XR)?

There is an increased risk of death for elderly patients with dementia related psychosis treated with antipsychotic drugs, Seroquel XR is not indicated for these patients. Additionally there is an increased risk of cerebrovascular accidents in this population while taking 2nd generation antipsychotics.

There is an increased risk of suicidal thoughts and behaviors in short-term studies in patients 24 and younger, patients starting this medication should notify their provider if they notice any negative changes in their mood.

Patients taking antipsychotic medications have an increased risk of Neuroleptic Malignant Syndrome (NMS). This condition is very rare but can be fatal so it is important to recognize the signs and symptoms of presentation. If you experience a high fever and muscle stiffness concurrently you should contact your physician as soon as possible.

Atypical antipsychotic medications are prime to inducing metabolic changes that include hyperglycemia, dyslipidemia, and body weight gain. Patients who are also diabetic should exercise caution when starting this medication as their insulin requirements may change.

In clinical trials there was found to be a risk of neutropenia/leukopenia in patients taking atypical antipsychotics. Patients with existing neutropenia should be monitored frequently and should discontinue Seroquel XR if their ANC <1000.
Patients on other medications that prolong their QT interval should have their QT interval evaluated prior to initiating Seroquel XR as it can also increase the QT interval.

See package label for a complete list of precautions

Side Effects

What are the side effects of Seroquel XR (Quetiapine XR)?

Some common side effects include:

  • Somnolence
  • Dry Mouth
  • Constipation
  • Dizziness
  • Increased Appetite
  • Dyspepsia
  • Weight Gain
  • Fatigue

Speak to your doctor for a full list of side effects.


Does this medication interact with other drugs, foods, or alcohol?

Patients on this medication should limit their exposure to alcohol given that it can exacerbate the potential cognitive and motor effects of the medication.

It is metabolized by CYP3A4, as a result, medications that are either inhibitors/inducers of CYP3A4 should be determined and the dose should be adjusted accordingly if concurrent use is necessary.

Ask your doctor or pharmacist if any of your current medications interact or if you are starting a new medication.


How should this medication be stored?

Seroquel should be stored at 25ºC (77ºF)

Pharmacist Tips

  • If you have any negative changes in your mood while taking this medication contact your physician.
  • Type 2 Diabetic patients who require insulin should expect their insulin requirements to change while on Seroquel XR. Frequent initial blood glucose checks after starting therapy should be completed as well as periodically throughout treatment.
  • Patients who have not recently had a lipid panel completed should have one done before starting Seroquel, and those patients with existing dyslipidemia should have frequent monitoring during treatment.
  • Seroquel can make you drowsy, so it is important to see how it first affects you prior to operating heavy machinery.
  • If you experience a high fever, excessive sweating, rigid muscles, confusion and/or changes in your breathing, heart rate, and blood pressure while taking this medication you should call your healthcare provider right away.
  • Do not discontinue this medication without first consulting your doctor, this medication can cause withdrawal effects (insomnia, headache, dizziness, irritability, nausea, vomiting).

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.


Save $10 on your first order!
Enter Canadian Pharmacy Online coupon code CPO10 to save $10 off your order. Minimum $50 order value. *Coupon codes are one-time use and cannot be combined.

Seroquel XR FAQ

How long does it take for Seroquel XR to kick in?

The sedative related side effect will likely happen after your first dose, however, to notice significant clinical benefits of the medication it may take up to 6 weeks.

What does Seroquel XR do to your brain?

The exact mechanism of Seroquel is not fully understood, but its efficacy is thought to stem from its ability to act as an antagonist to dopamine and serotonin (5HT2) receptors to provide benefit for patients being treated for schizophrenia. For patients being treated for MDD, its benefit is thought to stem from its ability to act as a norepinephrine antagonist. However, Seroquel is not just limited to acting on these receptors in the brain.

Is Seroquel XR used for sleep?

In some cases physicians will use the immediate release formulation of seroquel to treat insomnia in adults, however, given that there have not been adequate studies conducted there is not sufficient evidence to support this usage.

Is Seroquel similar to Xanax?

No, Seroquel and Xanax are different medications. Seroquel is an atypical antipsychotic whereas Xanax is a benzodiazepine and functions differently in the brain. Both medications, however, can make you drowsy.

How much weight do you gain on Seroquel?

The weight gain associated with Seroquel is generally dose dependent, in clinical trials patients reported a gain of > or = 7% of body weight anywhere from 3% to 10% of the time. The higher doses are responsible for greater incidence.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.