Synjardy (Empagliflozin/Metformin)

Synjardy can be ordered online through CanadianPharmacyOnline.com or by calling 1-800-828-4489 and speaking to customer support. The chat feature can also be used for support. For more information please visit the “How to Order” page.

Yes, a valid prescription from your doctor is required. Synjardy is a prescription medication and can only be sold with a prescription. To process your order, you will need to submit a prescription. The prescription can be emailed ([email protected]), faxed (1-800-416-8019), or uploaded. Alternatively, we can reach out to your doctor to attain a valid prescription if you would like.

A 3-month supply (90 days) is the maximum amount that can be ordered at one time. Refills are kept on file for future orders. The amount that can be ordered will be based on the directions and quantity indicated on the prescription from your provider.

Absolutely. All our partner pharmacies are fully licensed and certified in their respective countries. We ensure that your shopping experience is safe and secure with our Norton Shopping Guarantee. We operate just like your local pharmacy would, with our main priority being to provide you access to safe and affordable prescription medication.

Synjardy 12.5 mg/1000mg – 60 Tablets

• Average US retail price – $658.25
• Our Price – $129.00

At CanadianPharmacyOnline.com, we make sure to keep drug prices low. You can view the Synjardy cost savings below:

We provide brand Synjardy 12.5 mg/1000 mg tablets here at Canadian Pharmacy Online. A quantity of 60 tablets of Synjardy costs $129, which comes out to $2.15 per unit.

Below shows the price comparison of Synjardy at a quantity of 60 tablets between the average U.S. retail price and Canadian Pharmacy Online price.

Lowest Price Per Unit: $1.82/unit for Synjardy 12.5 mg/1000 mg tablets

The prices mentioned above are not processed through insurance. Although we cannot accept insurance, we will give you an official receipt which you can use to apply for reimbursement with your insurer. We are also unable to adjudicate with US insurance providers.

Drug prices are negotiated and regulated in Canada. Because the US is a free market economy, the price differs since pharmaceutical suppliers can charge what they deem appropriate for the product. As a result, we can offer lower prices to our patients as we supply medications from these countries.

Synjardy is not available as a generic alternative.

There is currently no generic alternative to Synjardy.

Once available on the market, there will be no difference between generic and brand Synjardy. Generic formulations of medications contain the same active ingredients and meet the same quality, strength, and purity standards as the brand formulation.

Yes. An email notification will be sent to you once the item has been shipped. We ship nationwide across the United States.

There are no standard shipping fees.

If a product of Canada is available then express shipping can be selected with an estimated delivery time of 3-5 business days. You have the option at the checkout page to select the express shipping option ($25) if available for that medication source.

Refilling your prescription is made easy with Canadian Pharmacy Online. You can sign into your online account and view your previous orders and see which prescriptions we have on file. Placing a refill order online is made simple by accessing the reorder section in your account.

You can also call us at 1-800-416-8019 and speak to customer support to place a refill. Our live chat is also a great place to connect with us to place a refill order while you are on the go.

We do not automatically refill prescriptions as there can be cases where you are no longer taking the medication, your doctor has changed your dose, etc. However, we provide a friendly refill reminder service. We will kindly notify you by phone or email as to the best time to place a refill order based on your prescription history.

What is Synjardy?

Synjardy is a prescription medication that is classified as a combination product containing a sodium-glucose co-transporter 2 (SGLT-2) inhibitor (empagliflozin) and a biguanide (metformin).

What is Synjardy used for?

It is used in adjunct with diet and exercise to achieve glycemic control in patients with type 2 diabetes that were unresponsive to empagliflozin or metformin monotherapy.

How does it work? 

The empagliflozin component inhibits SGLT2 which reduces the renal reabsorption of glucose resulting in increased glucose excretion. The metformin component increases peripheral glucose uptake and utilization to exert its glucose lowering effects.

How do I take Synjardy?  

Synjardy should be taken as directed by your doctor. It should be dosed with meals to lessen the chance of stomach upset. While taking this medication, check your blood sugar regularly; your doctor will also monitor your blood sugar through blood tests periodically. You may also need to take other diabetes medications along with Synjardy, refer to your doctor for your specific diabetes management plan.

What dosages are available?

Synjardy is available by brand-only 5 mg/500 mg, 5 mg/1000 mg, 12.5 mg/500 mg, and 12.5 mg/1000 mg tablets.

What is the recommended dosage?

The specific dosage formulation of Synjardy depends on how controlled your diabetes was on your previous diabetes medications but generally it is dosed twice daily with meals.

What is the maximum dosage?

The maximum recommended dosage is 12.5 mg/1000 mg twice daily.

What if I miss a dose?

Take the missed dose as soon as you remember unless it is close to the time you are due for your next dose. If that is the case, just wait until it is time for your next dose. Do not double your dose to compensate for your missed dose.

What should you know before you take Synjardy?

Avoid excessive alcohol use and use in patients with hepatic impairment or in hypoxic states as it may result in lactic acidosis

This medication may result in hypotension. Patients should be assessed for appropriate volume status prior to therapy.

Renal function should be monitored during therapy

Discontinue Synjardy temporarily if patient is to undergo radiologic studies requiring iodinated contrast materials or if surgery requires restriction of food and fluid intake

The risk for hypoglycemia is increased if Synjardy is combined with insulin products; the dose of insulin may need to be lowered

Risk for genital mycotic infections, urinary tract infections, and vitamin B-12 deficiency

Synjardy may increase your LDL levels; your doctor will monitor and treat as appropriate

Currently there are no clinical studies to establish conclusive evidence that Synjardy has macrovascular risk reduction

What are the side effects of Synjardy?

Some common side effects (≥5%) include:

• Urinary tract infection
• Female genital mycotic infections
• Diarrhea
• Nausea/vomiting
• Flatulence
• Abdominal discomfort
• Indigestion
• Asthenia
• Headache

Speak to your doctor for a full list of side effects.

Does this medication interact with other drugs, foods, or alcohol?

Use caution with cationic drugs that are eliminated by renal tubular secretion as they may reduce the elimination of metformin

How should this medication be stored?

Keep Synjardy in the original container and store it in a dry place at room temperature 15-30°C (59-86°F).

• Symptoms of lactic acidosis include: feeling very weak/tired, unusual muscle pain, trouble sleeping, cold sensations in your arms and legs, and slow heartbeat. If you experience any of these symptoms, immediately seek medical attention.
• There is a higher risk for experiencing lactic acidosis if you have renal impairment, liver impairment, have congestive heart failure, binge-drink alcohol, are dehydrated, have a history of heart attack, or are over the age of 80.
• Symptoms of hypoglycemia include: fatigue, sweating, fast heartbeat, hunger, irritability, and confusion. If you experience any of these symptoms, check your blood sugar.